Kazuo Shinozuka

Physicochemical properties of phospborothioate oligodeoxynucleotides

C.A. Stein, C. Subasinghe, Kazuo Shinozuka et al. · Nucleic Acids Research · 1988 · 580 citations · Full text

Nucleic Acid Chemistry, Biochemistry, Contrast Duplexes +11

Phosphorothioate analogs of oligodeoxynucleotides: inhibitors of replication and cytopathic effects of human immunodeficiency virus.

Makoto Matsukura, Kazuo Shinozuka, Gerald Zon et al. · Proceedings of the National Academy of Sciences · 1987 · 534 citations · Full text

Immunology, Nuclease-resistant Phosphorothioate Analogs, Molecular Biology +19

Regulation of viral expression of human immunodeficiency virus in vitro by an antisense phosphorothioate oligodeoxynucleotide against rev (art/trs) in chronically infected cells.

Makoto Matsukura, Gerald Zon, Kazuo Shinozuka et al. · Proceedings of the National Academy of Sciences · 1989 · 263 citations · Full text

Viral Replication, Immunology, Molecular Biology +20

Comparative inhibition of chloramphenicol acetyltransferase gene expression by antisense oligonucleotide analogues having alkyl phosphotriester, methylphosphonate and phosphorothioate linkages

Carol J. Marcus-Sekura, Amy M. Woerner, Kazuo Shinozuka et al. · Nucleic Acids Research · 1987 · 175 citations · Full text

Antisense Oligonucleotide Analogues, Viral Replication, Immunology +19

Phosphorothioate and normal oligodeoxyribonucleotides with 5′-linked acridine: characterization and preliminary kinetics of cellular uptake

C.A. Stein, Kazuyo Mori, S.L. Loke et al. · Gene · 1988 · 121 citations

Preliminary Kinetics, Biosynthesis, Nucleic Acid Chemistry +9