Trans-4-lodo,4′-boranyl-chalcone induces antitumor activity against malignant glioma cell lines in vitro and in vivo

In Vivo Activation of the p53 Pathway by Small-Molecule Antagonists of MDM2

Lyubomir T. Vassilev, Binh Thanh Vu, Bradford Graves et al. · Science · 2004 · 4.7K citations

Medicine, Oncology, Pharmacology +15

The MDM2-p53 interaction.

Ute M. Moll, Oleksi Petrenko · PubMed · 2003 · 789 citations

Life Sciences, Molecular Biology, Oncology +11

Small molecule RITA binds to p53, blocks p53–HDM-2 interaction and activates p53 function in tumors

Natalia Issaeva, Przemyslaw Bozko, Martin Enge et al. · Nature Medicine · 2004 · 744 citations

Medicine, Molecular Biology, Oncology +15

Cancer chemopreventive activity of Xanthohumol, a natural product derived from hop.

Clarissa Gerhäuser, Axel Alt, Amira M. Gamal‐Eldeen et al. · PubMed · 2002 · 412 citations

Medicine, Oncology, Pharmacology +16

Design, Synthesis, and Evaluation of Novel Boronic-Chalcone Derivatives as Antitumor Agents

Srinivas K. Kumar, Erin R. Hager, Catherine Pettit et al. · Journal of Medicinal Chemistry · 2003 · 302 citations

Medicine, Medicinal Chemistry, Oncology +9