Galactose-poly(ethylene glycol)-polyethylenimine for improved lung gene transfer

A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine.

Otmane Boussif, Frank Lezoualc’h, Maria Antonietta Zanta et al. · Proceedings of the National Academy of Sciences · 1995 · 6.2K citations

Pharmacy, Biotechnology, Pharmaceutics +17

PEGylated DNA/transferrin–PEI complexes: reduced interaction with blood components, extended circulation in blood and potential for systemic gene delivery

Manfred Ogris, Silvia Brunner, Susanne Schüller et al. · Gene Therapy · 1999 · 1.2K citations

Pharmacy, Bioengineering, Pharmaceutics +16

A Powerful Nonviral Vector for <i>In Vivo</i> Gene Transfer into the Adult Mammalian Brain: Polyethylenimine

Bassima Abdallah, Corinne Benoist, Daniel Goula et al. · Human Gene Therapy · 1996 · 542 citations

Life Sciences, Molecular Biology, Neuroscience +16

Optimized galenics improve in vitro gene transfer with cationic molecules up to 1000-fold.

Otmane Boussif, Maria Antonietta Zanta, Jean‐Paul Behr · PubMed · 1996 · 346 citations

Life Sciences, Biotechnology, Molecular Biology +9

Evaluation of polyether-polyethyleneimine graft copolymers as gene transfer agents

H-K Nguyen, Pierre Lemieux, Catherine Gebhart et al. · Gene Therapy · 2000 · 346 citations

Pharmacy, Bioengineering, Biotechnology +14