Evaluation of polyether-polyethyleneimine graft copolymers as gene transfer agents

A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine.

Otmane Boussif, Frank Lezoualc’h, Maria Antonietta Zanta et al. · Proceedings of the National Academy of Sciences · 1995 · 6.2K citations

Pharmacy, Biotechnology, Pharmaceutics +17

Micellization of Poly(ethylene oxide)-Poly(propylene oxide)-Poly(ethylene oxide) Triblock Copolymers in Aqueous Solutions: Thermodynamics of Copolymer Association

Paschalis Alexandridis, Josef F. Holzwarth, T. Alan Hatton · Macromolecules · 1994 · 1.8K citations

Natural Sciences, Chemistry, Materials Science +17

The influence of polymer structure on the interactions of cationic polymers with DNA and morphology of the resulting complexes

MX Tang, FC Szoka · Gene Therapy · 1997 · 804 citations

Natural Sciences, Biochemistry, Chemistry +15

Improved DNA: liposome complexes for increased systemic delivery and gene expression

Nancy Smyth Templeton, Danilo D. Lasiç, Peter M. Frederik et al. · Nature Biotechnology · 1997 · 740 citations

Pharmacy, Molecular Biology, Molecular Pharmaceutics +16

The size of DNA/transferrin-PEI complexes is an important factor for gene expression in cultured cells

Manfred Ogris, Peter Steinlein, Malgorzata Kursa et al. · Gene Therapy · 1998 · 572 citations

Life Sciences, Cell Biology, Molecular Biology +7