Proceedings of the National Academy of Sciences · 2006 · 207 citations · 34 references
Life SciencesCell BiologyMolecular BiologyChromatin BiologyChromatin StructureTranscriptional RegulationChromatinChromatin ArchitectureHistone ChaperonesHistone ProteinsNucleosome OrganizationNucleosome StructureChromatin RemodelingChromatin Remodeling At PromotersChromatin Remodeling ComplexesHistone Chaperone ComplexesHistone H2a-h2b DimerNucleosome DisassemblyNucleosome Remodeling ComplexesTranscriptional Activation
The RSC chromatin-remodeling complex completely disassembles a nucleosome in the presence of the histone chaperone Nap1 and ATP. Disassembly occurs in a stepwise manner, with the removal of H2A/H2B dimers, followed by the rest of the histones and the release of naked DNA. RSC and related chromatin-remodeling complexes may be responsible for the removal of promoter nucleosomes during transcriptional activation in vivo.
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Stimulation of GAL4 Derivative Binding to Nucleosomal DNA by the Yeast SWI/SNF Complex
Jacques Côté, Janet Quinn, Jerry L. Workman et al. · Science · 1994 · 862 citations
RSC, an Essential, Abundant Chromatin-Remodeling Complex
Bradley R. Cairns, Yahli Lorch, Yang Li et al. · Cell · 1996 · 678 citations · Full text
The RCAF complex mediates chromatin assembly during DNA replication and repair
Jessica K. Tyler, Christopher R. Adams, Shaw-Ree Chen et al. · Nature · 1999 · 547 citations