Concepedia

Nucleosome Disassembly

Nucleosome Disassembly is a molecular process in chromatin dynamics whereby a nucleosome, the fundamental repeating unit of chromatin, is dissociated into its constituent histone proteins and free DNA through the action of ATP-dependent chromatin remodeling complexes, histone chaperones, or post-translational modifications, thereby facilitating access to genomic DNA for transcription, replication, or repair.

130

Publications

10.4K

Citations

580

Authors

215

Institutions

Publications per year

2017–2026

30

Parents

Publications

130

Nucleosome disruption and enhancement of activator binding by a human SW1/SNF complex

Hyockman Kwon, Anthony N. Imbalzano, Paul A. Khavari et al. · Nature · 1994 · 783 citations

, , +14

Mechanical disruption of individual nucleosomes reveals a reversible multistage release of DNA

Brent D. Brower‐Toland, Corey L. Smith, Richard Cheng-I Yeh et al. · Proceedings of the National Academy of Sciences · 2002 · 498 citations

, , +15

PAD4 mediated histone hypercitrullination induces heterochromatin decondensation and chromatin unfolding to form neutrophil extracellular trap-like structures

Marc Leshner, Shu Wang, Carrie Lewis et al. · Frontiers in Immunology · 2012 · 468 citations · Full text

, , +17

Rapid, Transcription-Independent Loss of Nucleosomes over a Large Chromatin Domain at Hsp70 Loci

Steven J. Petesch, John T. Lis · Cell · 2008 · 316 citations · Full text

, , +15

In vivo studies on the dynamics of histone-DNA interaction: evidence for nucleosome dissolution during replication and transcription and a low level of dissolution independent of both

Vaughn Jackson · Biochemistry · 1990 · 258 citations

, , +15

1–5 of 130

Authors

580

  1. BB
    Blaine Bartholomew

    Southern Illinois University School of Medicine, United States

    6 publications · 617 citations

    6

    h-index

  2. KL
    Karolin Luger

    Colorado State University, United States

    6 publications · 485 citations

    6

    h-index

  3. KT
    Katalin Tóth

    University of Debrecen, Hungary

    4 publications · 477 citations

    4

    h-index

  4. MG
    Michael G. Poirier

    The Ohio State University, United States

    4 publications · 395 citations

    4

    h-index

  5. ML
    Mekonnen Lemma Dechassa

    Southern Illinois University School of Medicine, United States

    3 publications · 306 citations

    3

    h-index

1–5 of 580

Institutions

215

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    10 h-index

    27 publications

    5K citations

  2. Cornell University

    Ithaca, United States

    6 h-index

    23 publications

    5K citations

  3. Karolinska Institutet

    Stockholm, Sweden

    6 h-index

    23 publications

    1.8K citations

  4. Southern Illinois University School of Medicine

    Springfield, United States

    5 h-index

    15 publications

    1.5K citations

  5. The Ohio State University

    Columbus, United States

    5 h-index

    10 publications

    1K citations

  6. Pennsylvania State University

    State College, United States

    5 h-index

    17 publications

    4.3K citations

  7. Cancer Genetics (United States)

    Rutherford, United States

    5 h-index

    13 publications

    823 citations

  8. German Cancer Research Center

    Heidelberg, Germany

    4 h-index

    17 publications

    2.6K citations

1–8 of 215

Venues

  1. Proceedings of the National Academy of Sciences

    PNAS · 15 publications · 1.8K citations

    15

    h-index

  2. Nucleic Acids Research

    14 publications · 736 citations

    13

    h-index

  3. Journal of Biological Chemistry

    JBC · 13 publications · 746 citations

    13

    h-index

  4. Molecular and Cellular Biology

    MCB · 11 publications · 926 citations

    11

    h-index

  5. Biochemistry

    5 publications · 388 citations

    5

    h-index

1–5