A concise and efficient solid-phase synthesis of 2-amino-4(3H)-quinazolinones

Quinazolineacetic acids and related analogs as aldose reductase inhibitors

Michael S. Malamas, Jane Millen · Journal of Medicinal Chemistry · 1991 · 278 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +8

Antihypertensive 2-amino-4(3H)-quinazolinones

H Hess, Timothy H. Cronin, Alexander Scriabine · Journal of Medicinal Chemistry · 1968 · 171 citations

Pharmacy, Medicinal Chemistry, Pharmacology +6

Design of thymidylate synthase inhibitors using protein crystal structures: the synthesis and biological evaluation of a novel class of 5-substituted quinazolinones

Stephen E. Webber, Ted M. Bleckman, John J. Attard et al. · Journal of Medicinal Chemistry · 1993 · 161 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +10

A mild and efficient method for the preparation of guanidines

Michael A. Poss, Edwin J. Iwanowicz, Joyce A. Reid et al. · Tetrahedron Letters · 1992 · 132 citations

Pharmacy, Medicinal Chemistry, Nucleic Acid Chemistry +2

The Chemistry of Isatoic Anhydride

Gary M. Coppola · Synthesis · 1980 · 129 citations

Natural Sciences, Chemistry, Medicinal Chemistry +7