Hyaluronic acid decorated lipid nanocarrier for MDR modulation and CD-44 targeting in colon adenocarcinoma

Overexpression of multidrug resistance-associated protein (MRP) increases resistance to natural product drugs.

Caroline E. Grant, Gunnar Valdimarsson, David R. Hipfner et al. · PubMed · 1994 · 635 citations

Medicine, Cancer Biology, Oncology +16

Metabolic fate of irinotecan in humans: correlation of glucuronidation with diarrhea.

E Gupta, Timothy M. Lestingi, Rosemarie Mick et al. · PubMed · 1994 · 506 citations

Pharmacy, Pharmacokinetics, Pharmacology +14

Optimal Structure Requirements for Pluronic Block Copolymers in Modifying P-glycoprotein Drug Efflux Transporter Activity in Bovine Brain Microvessel Endothelial Cells

Elena V. Batrakova, Shu Li, Valery Yu. Alakhov et al. · Journal of Pharmacology and Experimental Therapeutics · 2003 · 264 citations

Medicine, Biochemistry, Pharmacology +17

Inhibition of Fatty Acid Synthase Attenuates CD44-Associated Signaling and Reduces Metastasis in Colorectal Cancer

Yekaterina Y. Zaytseva, Piotr Rychahou, Pat Gulhati et al. · Cancer Research · 2012 · 217 citations · Full text

Life Sciences, Cell Biology, Oncology +16

Development of an Itraconazole-loaded nanostructured lipid carrier (NLC) formulation for pulmonary application

Jana Pardeike, Sabrina Weber, Thomas Haber et al. · International Journal of Pharmaceutics · 2011 · 216 citations

Pharmacy, Pharmaceutics, Pharmacology +14