Concepedia

Arylglycine derivatives as potent transient receptor potential melastatin 8 (TRPM8) antagonists

Bin Zhu, Mingde Xia, Xiaoqing Xu, Donald Ludovici, Manomi A. Tennakoon, Mark A. Youngman, Jay M. Matthews, Scott L. Dax, Raymond W. Colburn, Tasha L. Hutchinson,

Bioorganic & Medicinal Chemistry Letters · 2013 · 27 citations · 19 references

DOIFull text

Open access

Concepts

References

19

Identification of a cold receptor reveals a general role for TRP channels in thermosensation

David D. McKemy, Werner Neuhausser, David Julius · Nature · 2002 · 2.7K citations

, , +16

A TRP Channel that Senses Cold Stimuli and Menthol

Andrea Peier, Aziz Moqrich, Anne C. Hergarden et al. · Cell · 2002 · 2.3K citations · Full text

, , +14

The menthol receptor TRPM8 is the principal detector of environmental cold

Diana M. Bautista, Jan Siemens, Joshua Glazer et al. · Nature · 2007 · 1.4K citations

, , +7

TRPM8 Is Required for Cold Sensation in Mice

Ajay Dhaka, Amber N. Murray, Jayanti Mathur et al. · Neuron · 2007 · 925 citations · Full text

, , +12

Attenuated Cold Sensitivity in TRPM8 Null Mice

Raymond W. Colburn, Mary Lou Lubin, Dennis J. Stone et al. · Neuron · 2007 · 758 citations · Full text

, , +6