Concepedia

In vitro cytotoxicity of 5-aminosubstituted 20( S )-camptothecins. part 1

Duvvuri Subrahmanyam, Vedula M. Sarma, A. Venkateswarlu, T. V. R. S. Sastry, Archana P. Kulakarni, D. Srinivasa Rao, K. Vasumathi Reddy

Bioorganic & Medicinal Chemistry · 1999 · 24 citations · 27 references

DOI

Concepts

References

27

Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I.

Y H Hsiang, Robert Hertzberg, Sidney M. Hecht et al. · Journal of Biological Chemistry · 1985 · 2.4K citations · Full text

, , +15

Plant Antitumor Agents. I. The Isolation and Structure of Camptothecin, a Novel Alkaloidal Leukemia and Tumor Inhibitor from Camptotheca acuminata<sup>1,2</sup>

Monroe E. Wall, Mansukh C. Wani, Clarence Cook et al. · Journal of the American Chemical Society · 1966 · 2.2K citations

, , +8

Some practical considerations and applications of the national cancer institute in vitro anticancer drug discovery screen

Michael R. Boyd, Kenneth D. Paull · Drug Development Research · 1995 · 1.6K citations

, , +12

Display and Analysis of Patterns of Differential Activity of Drugs Against Human Tumor Cell Lines: Development of Mean Graph and COMPARE Algorithm

Kenneth D. Paull, Robert H. Shoemaker, Louis Hodes et al. · JNCI Journal of the National Cancer Institute · 1989 · 969 citations

, , +16

Synthesis of water-soluble (aminoalkyl)camptothecin analogs: inhibition of topoisomerase I and antitumor activity

William D. Kingsbury, Jeffrey C. Boehm, Dalia R. Jakas et al. · Journal of Medicinal Chemistry · 1991 · 516 citations

, , +10