Concepedia

Geldanamycin, a HSP90 inhibitor, attenuates the hypoxia-induced vascular endothelial growth factor expression in retinal pigment epithelium cells in vitro

Wen‐Chuan Wu, Y. H. Kao, Pei‐Shin Hu, Jiun-Hwan Chen

Experimental Eye Research · 2007 · 39 citations · 36 references

DOI

Concepts

References

36

Hsp90 Regulates a von Hippel Lindau-independent Hypoxia-inducible Factor-1α-degradative Pathway

Jennifer S. Isaacs, Yunjin Jung, Edward G. Mimnaugh et al. · Journal of Biological Chemistry · 2002 · 659 citations · Full text

, , +15

Vascular endothelial growth factor/vascular permeability factor is temporally and spatially correlated with ocular angiogenesis on a primate model

Miller Jw · UCL Discovery (University College London) · 1994 · 584 citations

, , +13

The Amino-terminal Domain of Heat Shock Protein 90 (hsp90) That Binds Geldanamycin Is an ATP/ADP Switch Domain That Regulates hsp90 Conformation

James P. Grenert, W. Patrick Sullivan, Patrick Fadden et al. · Journal of Biological Chemistry · 1997 · 570 citations · Full text

, , +16

Hypoxic Regulation of Vascular Endothelial Growth Factor in Retinal Cells

Lloyd Paul Aiello · Archives of Ophthalmology · 1995 · 561 citations

, , +17

The heat-shock response: regulation and function of heat-shock proteins and molecular chaperones.

Ryo Morimoto, Michael Kline, David N. Bimston et al. · PubMed · 1997 · 437 citations

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