Concepedia

Molecular Mechanism of Nuclear Translocation of an Orphan Nuclear Receptor, SXR

Katsuyoshi Kawana, Togo Ikuta, Yasuhito Kobayashi, Osamu Gotoh, Ken Takeda, Kaname Kawajiri

Molecular Pharmacology · 2003 · 110 citations · 33 references

DOI

Concepts

References

33

The neighbor-joining method: a new method for reconstructing phylogenetic trees.

Naruya Saitou, M Nei · Molecular Biology and Evolution · 1987 · 60.5K citations · Full text

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A signature motif in transcriptional co-activators mediates binding to nuclear receptors

David M. Heery, Eric Kalkhoven, Susan Hoare et al. · Nature · 1997 · 2.1K citations

, , +16

The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions.

J�rgen Lehmann, David D. McKee, M. A. Watson et al. · Journal of Clinical Investigation · 1998 · 1.6K citations · Full text

, , +14

An Orphan Nuclear Receptor Activated by Pregnanes Defines a Novel Steroid Signaling Pathway

Steven A. Kliewer, John T. Moore, Laura Wade et al. · Cell · 1998 · 1.5K citations · Full text

, , +16

The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity

Jeff L. Staudinger, Bryan Goodwin, Stacey A. Jones et al. · Proceedings of the National Academy of Sciences · 2001 · 1.4K citations · Full text

, , +13