Expression of bcl2 family proteins and active caspase 3 in classical Hodgkin's lymphomas

Endonuclease G is an apoptotic DNase when released from mitochondria

Lily Y. Li, Xu Luo, Xiaodong Wang · Nature · 2001 · 1.7K citations

Life Sciences, Cell Biology, Molecular Biology +7

Constitutive nuclear factor-kappaB-RelA activation is required for proliferation and survival of Hodgkin's disease tumor cells.

Ralf C. Bargou, Florian Emmerich, Daniel Krappmann et al. · Journal of Clinical Investigation · 1997 · 765 citations · Full text

Medicine, Cell Biology, Oncology +15

Aberrantly expressed c‐Jun and JunB are a hallmark of Hodgkin lymphoma cells, stimulate proliferation and synergize with NF‐κB

Stephan Mathas · The EMBO Journal · 2002 · 377 citations · Full text

Medicine, Molecular Biology, Oncology +14

Constitutive NF-κB maintains high expression of a characteristic gene network, including CD40, CD86, and a set of antiapoptotic genes in Hodgkin/Reed-Sternberg cells

M. Hinz, Peter Löser, Stephan Mathas et al. · Blood · 2001 · 259 citations

Life Sciences, Cell Biology, Molecular Biology +17

Nuclear Factor κB–dependent Gene Expression Profiling of Hodgkin's Disease Tumor Cells, Pathogenetic Significance, and Link to Constitutive Signal Transducer and Activator of Transcription 5a Activity

M. Hinz, Petra Lemke, Ioannis Anagnostopoulos et al. · The Journal of Experimental Medicine · 2002 · 259 citations

Medicine, Cancer Biology, Oncology +17