Synthesis and evaluation of non-basic inhibitors of urokinase-type plasminogen activator (uPA)

Tumor invasion through the human amniotic membrane: Requirement for a proteinase cascade

Paolo Mignatti, E. Robbins, Daniel B. Rifkin · Cell · 1986 · 750 citations

Life Sciences, Molecular Biology, Oncology +16

Discovery of the Novel Antithrombotic Agent 5-Chloro-<i>N</i>-({(5<i>S</i>)-2-oxo-3- [4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)thiophene- 2-carboxamide (BAY 59-7939):  An Oral, Direct Factor Xa Inhibitor

Susanne Roehrig, Alexander Straub, Jens Pohlmann et al. · Journal of Medicinal Chemistry · 2005 · 433 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +10

Cyclohexylcarbamic Acid 3‘- or 4‘-Substituted Biphenyl-3-yl Esters as Fatty Acid Amide Hydrolase Inhibitors:  Synthesis, Quantitative Structure−Activity Relationships, and Molecular Modeling Studies

Marco Mor, Silvia Rivara, Alessio Lodola et al. · Journal of Medicinal Chemistry · 2004 · 274 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Urokinase overproduction results in increased skeletal metastasis by prostate cancer cells in vivo.

Abderrahim Achbarou, Stéphanie Kaiser, Gilles Tremblay et al. · PubMed · 1994 · 225 citations

Medicine, Molecular Biology, Oncology +14

Preparation of N,N,N′-tris(trimethylsilyl)amidines; a convenient route to unsubstituted amidines

Renè T. Boeré, Richard T. Oakley, Robert W. Reed · Journal of Organometallic Chemistry · 1987 · 191 citations

Natural Sciences, Chemistry, Medicinal Chemistry +6