Novel and potent calcium-sensing receptor antagonists: Discovery of (5R)-N-[1-ethyl-1-(4-ethylphenyl)propyl]-2,7,7-trimethyl-5-phenyl-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide monotosylate (TAK-075) as an orally active bone anabolic agent

Publication | Open Access

DOI Full Paper Access

Citations

References

2011

Year

Masato Yoshida, Akira Mori, Shinji Morimoto, Etsuo Kotani, Masahiro Oka, Kohei Notoya, Haruhiko Makino, Midori Ono, Mikio Shirasaki, Norio Tada,

Bioorganic & Medicinal Chemistry

Medicinal ChemistryMedicinePharmacological AgentPharmacotherapyBiomedical EngineeringPharmacologyOsteoporosisBone MetabolismOsteocalcinDrug Discovery