Frequency of CYP2C9 alleles in Koreans and their effects on losartan pharmacokinetics

Validation of Methods for CYP2C9 Genotyping: Frequencies of Mutant Alleles in a Swedish Population

Ümit Yaşar, Erik Eliasson, Marja-Liisa Dahl et al. · Biochemical and Biophysical Research Communications · 1999 · 252 citations

Life Sciences, Genetics, Molecular Genetics +7

Allele and genotype frequencies of CYP2C9, CYP2C19 and CYP2D6 in an Italian population

M.G. Scordo · Pharmacological Research · 2004 · 227 citations

Life Sciences, Biology, Genetics +11

Pharmacokinetics/Genotype Associations for Major Cytochrome P450 Enzymes in Native and First- and Third-generation Japanese Populations: Comparison With Korean, Chinese, and Caucasian Populations

S P Myrand, Kanako Sekiguchi, MZ Man et al. · Clinical Pharmacology & Therapeutics · 2008 · 225 citations

Medicine, Pharmacokinetics, Pharmacology +17

Genetic Variation in Metabolizing Enzyme and Transporter Genes: Comprehensive Assessment in 3 Major East Asian Subpopulations With Comparison to Caucasians and Africans

Michael Man, Mark W. Farmen, Carmen M. Dumaual et al. · The Journal of Clinical Pharmacology · 2010 · 216 citations

Veterinary Medicine, Genetics, Pharmacology +17

Biotransformation of losartan to its active carboxylic acid metabolite in human liver microsomes. Role of cytochrome P4502C and 3A subfamily members.

Ralph A. Stearns, Probir Chakravarty, R Chen et al. · Drug Metabolism and Disposition · 1995 · 208 citations

Medicine, Biochemistry, Pharmacology +17