A new delivery system for auristatin in STxB-drug conjugate therapy

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Jagath R. Junutula, Helga Raab, Suzanna Clark et al. · Nature Biotechnology · 2008 · 1.4K citations

Pharmacy, Pharmaceutics, Pharmacology +16

Development of potent monoclonal antibody auristatin conjugates for cancer therapy

Svetlana O. Doronina, Brian E. Toki, Michael Torgov et al. · Nature Biotechnology · 2003 · 1.2K citations

Pharmacy, Medicinal Chemistry, Oncology +14

Aberrant glycosylation in cancer cell membranes as focused on glycolipids: overview and perspectives.

Sen‐itiroh Hakomori · PubMed · 1985 · 807 citations

Life Sciences, Biochemistry, Oncology +14

Ado-trastuzumab Emtansine (T-DM1): An Antibody–Drug Conjugate (ADC) for HER2-Positive Breast Cancer

John M. Lambert, Ravi Chari · Journal of Medicinal Chemistry · 2014 · 532 citations

Medicine, Oncology, Pharmacology +17

Enhanced Activity of Monomethylauristatin F through Monoclonal Antibody Delivery:  Effects of Linker Technology on Efficacy and Toxicity

Svetlana O. Doronina, Brian A. Mendelsohn, Tim D. Bovee et al. · Bioconjugate Chemistry · 2005 · 512 citations

Pharmacy, Oncology, Pharmacology +17