Concepedia

Total synthesis of (±)-aspercyclide A and its C19 methyl ether

James L. Carr, D.A. Offermann, M.D. Holdom, Philip Dusart, Andrew J. P. White, Andrew J. Beavil, Robin J. Leatherbarrow, Stephen D. Lindell, Brian J. Sutton, Alan C. Spivey

Chemical Communications · 2009 · 33 citations · 19 references

DOIFull text

Open access

Concepts

Abstract

The total syntheses of (+/-)-aspercyclide A (1) and its C19 methyl ether (15a) featuring Heck-Mizoroki macrocyclisation to form the 11-membered (E)-styrenyl biaryl ether lactone core are described.

References

19

Catalytic Direct Arylation with Aryl Chlorides, Bromides, and Iodides:  Intramolecular Studies Leading to New Intermolecular Reactions

Louis‐Charles Campeau, Mathieu Parisien, Annie Jean et al. · Journal of the American Chemical Society · 2005 · 677 citations

, , +16

Copper-Catalyzed Halogen Exchange in Aryl Halides:  An Aromatic Finkelstein Reaction

Artis Klapars, Stephen L. Buchwald · Journal of the American Chemical Society · 2002 · 428 citations

, , +15

High-affinity oligonucleotide ligands to human IgE inhibit binding to Fc ε receptor I

T W Wiegand, P. Brock Williams, Stephen C. Dreskin et al. · The Journal of Immunology · 1996 · 350 citations · Full text

, , +16

The Heck–Mizoroki cross-coupling reaction: a mechanistic perspective

Jonathan P. Knowles, Andrew Whiting · Organic & Biomolecular Chemistry · 2006 · 295 citations

, , +7

Metal-catalysed halogen exchange reactions of aryl halides

Tom D. Sheppard · Organic & Biomolecular Chemistry · 2009 · 134 citations · Full text

, , +14