Robin J. Leatherbarrow

Validation of N-myristoyltransferase as an antimalarial drug target using an integrated chemical biology approach

Megan H. Wright, Barbara Clough, M.D. Rackham et al. · Nature Chemistry · 2013 · 216 citations · Full text

Drug Target, Biochemistry, Antimalarial Drug Target +6

Effector functions of a monoclonal aglycosylated mouse IgG2a: Binding and activation of complement component C1 and interaction with human monocyte Fc receptor

Robin J. Leatherbarrow, Thomas W. Rademacher, Raymond A. Dwek et al. · Molecular Immunology · 1985 · 196 citations

Inflammation, Complement System, Immune Effector Functions +11

Transition-state stabilization in the mechanism of tyrosyl-tRNA synthetase revealed by protein engineering.

Robin J. Leatherbarrow, Alan R. Fersht, Greg Winter · Proceedings of the National Academy of Sciences · 1985 · 179 citations · Full text

Transition State, Principal Catalytic Factor, Transition-state Stabilization +15

Kinetics of Protein-Protein Interactions at the Surface of an Optical Biosensor

P. R. Edwards, Anita Gill, Mike Hoare et al. · Analytical Biochemistry · 1995 · 179 citations

Protein Chemistry, Protein-protein Interactions, Biochemistry +7

Structure-activity relationships in engineered proteins: analysis of use of binding energy by linear free energy relationships

Alan R. Fersht, Robin J. Leatherbarrow, Timothy N. C. Wells · Biochemistry · 1987 · 155 citations