Hepatitis B Virus Replication Is Regulated by the Acetylation Status of Hepatitis B Virus cccDNA-Bound H3 and H4 Histones

Viral Clearance Without Destruction of Infected Cells During Acute HBV Infection

Luca G. Guidotti, Rosemary Rochford, Josan Chung et al. · Science · 1999 · 1.2K citations

Life Sciences, Immunology, Infectious Diseases +16

Nucleotide sequence of the hepatitis B virus genome (subtype ayw) cloned in E. coli

Francis Galibert, Elisabeth Mandart, Françoise Fitoussi et al. · Nature · 1979 · 987 citations · Full text

Life Sciences, Molecular Biology, Molecular Genetics +14

Persistence of cccDNA during the natural history of chronic hepatitis B and decline during adefovir dipivoxil therapy1 ☆

Bettina Werle–Lapostolle, Scott Bowden, Stephen Locarnini et al. · Gastroenterology · 2004 · 899 citations · Full text

Medicine, Infectious Diseases, Pharmacology +14

The hepatitis B virus persists for decades after patients' recovery from acute viral hepatitis despite active maintenance of a cytotoxic T–lymphocyte response

Barbara Rehermann, Carlo Ferrari, C Pasquinelli et al. · Nature Medicine · 1996 · 849 citations

Life Sciences, Immunology, Infectious Diseases +10

Methyltransferase Recruitment and DNA Hypermethylation of Target Promoters by an Oncogenic Transcription Factor

Luciano Di Croce, Veronica A. Raker, Massimo Corsaro et al. · Science · 2002 · 780 citations

Medicine, Genetics, Molecular Biology +17