IFN-α inhibits HBV transcription and replication in cell culture and in humanized mice by targeting the epigenetic regulation of the nuclear cccDNA minichromosome

Laura Belloni, Lena Allweiss, Francesca Guerrieri, +7

Journal of Clinical Investigation

Viral ReplicationActive CccdnaImmunologyMolecular BiologyCell Culture +20

Nuclear HBx binds the HBV minichromosome and modifies the epigenetic regulation of cccDNA function

Laura Belloni, Teresa Pollicino, Francesca De Nicola, +5

Proceedings of the National Academy of Sciences

Viral ReplicationEpigenetic ChangeCccdna FunctionMolecular BiologyHbv Cccdna +18

Hepatitis B virus X protein is essential to initiate and maintain virus replication after infection

Julie Lucifora, Silke Arzberger, David Durantel, +6

Journal of Hepatology

Virus ReplicationViral ReplicationMolecular VirologyViral PersistenceViral Hepatitis +7

Hepatitis B Virus Replication Is Regulated by the Acetylation Status of Hepatitis B Virus cccDNA-Bound H3 and H4 Histones

Teresa Pollicino, Laura Belloni, G. Raffa, +4

Gastroenterology

ChromatinViral ReplicationViral HepatitisGeneticsNatural Sciences +9

Early intra-intensive care unit psychological intervention promotes recovery from post traumatic stress disorders, anxiety and depression symptoms in critically ill patients

Adriano Peris, Manuela Bonizzoli, Dario Iozzelli, +11

Critical Care

Differential regulation of E2F1 apoptotic target genes in response to DNA damage

Natalia Pediconi, Alessandra Ianari, Antonio Costanzo, +9

Nature Cell Biology

Reductive StressGenome InstabilityDna DamageCell RegulationGenetics +7

Hepatitis B protein HBx binds the DLEU2 lncRNA to sustain cccDNA and host cancer-related gene transcription

Debora Salerno, Letizia Chiodo, Vincenzo Alfano, +10

Gut

IL6 Inhibits HBV Transcription by Targeting the Epigenetic Control of the Nuclear cccDNA Minichromosome

G.A. Palumbo, C. Scisciani, Natalia Pediconi, +8

PLoS ONE

Viral ReplicationImmunologyHbv CccdnaInnate ImmunityEpigenetic Control +18

hSirT1-Dependent Regulation of the PCAF-E2F1-p73 Apoptotic Pathway in Response to DNA Damage

Natalia Pediconi, Francesca Guerrieri, Stefania Vossio, +6

Molecular and Cellular Biology

Dna DamageApoptosisCell DeathMolecular BiologyEpigenetics +20

Genome-wide identification of direct HBx genomic targets

Francesca Guerrieri, Laura Belloni, Daniel D’Andrea, +8

BMC Genomics