Francesca Guerrieri

IFN-α inhibits HBV transcription and replication in cell culture and in humanized mice by targeting the epigenetic regulation of the nuclear cccDNA minichromosome

Laura Belloni, Lena Allweiss, Francesca Guerrieri et al. · Journal of Clinical Investigation · 2012 · 563 citations · Full text

Viral Replication, Active Cccdna, Immunology +22

Nuclear HBx binds the HBV minichromosome and modifies the epigenetic regulation of cccDNA function

Laura Belloni, Teresa Pollicino, Francesca De Nicola et al. · Proceedings of the National Academy of Sciences · 2009 · 478 citations · Full text

Viral Replication, Epigenetic Change, Cccdna Function +20

Targeting mitochondrial dysfunction can restore antiviral activity of exhausted HBV-specific CD8 T cells in chronic hepatitis B

Paola Fisicaro, Valeria Barili, Barbara Montanini et al. · Nature Medicine · 2017 · 337 citations

Viral Persistence, Hepatology, Mitochondrial Dysfunction +9

Enteric Delivery of Regenerating Family Member 3 alpha Alters the Intestinal Microbiota and Controls Inflammation in Mice With Colitis

Marion Darnaud, Alexandre Dos Santos, Patrick Gonzalez et al. · Gastroenterology · 2017 · 148 citations · Full text

Hepatitis B protein HBx binds the DLEU2 lncRNA to sustain cccDNA and host cancer-related gene transcription

Debora Salerno, Letizia Chiodo, Vincenzo Alfano et al. · Gut · 2020 · 139 citations · Full text