Beta1-Adrenoceptor Polymorphism Predicts Flecainide Action in Patients with Atrial Fibrillation

Amir M. Nia, Evren Caglayan, Natig Gassanov, Tom Zimmermann, Orhan Aslan, Martin Hellmich, Erland Erdmann, Stephan Rosenkranz, Fikret Er

PLoS ONE · 2010 · 20 citations · 32 references

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Abstract

The beta(1)AR Arg389Arg genotype is associated with increased flecainide potency and higher heart rate during atrial fibrillation. The Arg389Gly-Ser49Gly genotype might be of predictive value for atrial fibrillation.

References

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