Uveal melanoma expression of indoleamine 2,3-deoxygenase: Establishment of an immune privileged environment by tryptophan depletion

Prevention of Allogeneic Fetal Rejection by Tryptophan Catabolism

David H. Munn, Min Zhou, John T. Attwood et al. · Science · 1998 · 2.6K citations

Life Sciences, Biochemistry, Immunology +16

Evidence for a tumoral immune resistance mechanism based on tryptophan degradation by indoleamine 2,3-dioxygenase

Catherine Uyttenhove, Luc Pilotte, Ivan Théate et al. · Nature Medicine · 2003 · 2.3K citations

Life Sciences, Cancer Biology, Immunology +11

Inhibition of  T Cell Proliferation by Macrophage Tryptophan Catabolism

David H. Munn, Ebrahim Shafizadeh, John T. Attwood et al. · The Journal of Experimental Medicine · 1999 · 1.6K citations · Full text

Life Sciences, Cell Biology, Immunology +17

Tryptophan-derived Catabolites Are Responsible for Inhibition of T and Natural Killer Cell Proliferation Induced by Indoleamine 2,3-Dioxygenase

Guido Frumento, Rita Rotondo, Michela Tonetti et al. · The Journal of Experimental Medicine · 2002 · 1.1K citations · Full text

Life Sciences, Biochemistry, Immunology +16

Prognostic value of tumor infiltrating lymphocytes in the vertical growth phase of primary cutaneous melanoma

Claudio G. Clemente, Martín C. Mihm, Rosaria Bufalino et al. · Cancer · 1996 · 1.1K citations · Full text

Medicine, Dermatology, Pathology +16