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Peptidomimetic aminomethylene ketone inhibitors of interleukin-1β-converting enzyme (ICE)

Graeme Semple, Doreen M. Ashworth, Andrzej R. Batt, Andrew Baxter, D. W. M. BENZIES, Lucy H. Elliot, Declan Evans, Richard J. Franklin, Peter Hudson, Paul D. Jenkins,

Bioorganic & Medicinal Chemistry Letters · 1998 · 30 citations · 6 references

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6

A novel heterodimeric cysteine protease is required for interleukin-1βprocessing in monocytes

Nancy A. Thornberry, Herbert G. Bull, Jimmy Calaycay et al. · Nature · 1992 · 2.6K citations

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Interleukin-1 and interleukin-1 antagonism

CA Dinarello · Blood · 1991 · 2.3K citations · Full text

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First Examples of Peptidomimetic Inhibitors of Interleukin-1β Converting Enzyme

Roland E. Dolle, Catherine Prouty, C. V. C. Prasad et al. · Journal of Medicinal Chemistry · 1996 · 44 citations

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PYRIDONE-BASED PEPTIDOMIMETIC INHIBITORS OF INTERLEUKIN-1β-CONVERTING ENZYME (ICE)

Graeme Semple, Doreen M. Ashworth, Graham R. Baker et al. · Bioorganic & Medicinal Chemistry Letters · 1997 · 30 citations

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Structure-based design of non-peptidic pyridone aldehydes as inhibitors of interleukin-1β converting enzyme

Julian M.C. Golec, Michael D. Mullican, Mark A. Murcko et al. · Bioorganic & Medicinal Chemistry Letters · 1997 · 25 citations

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