Concepedia

Graeme Semple

GS

46

Publications

2.3K

Citations

29

H-Index

1984

Active since

Affiliations

Arena Pharmaceuticals (United States)(Current)

Merck & Co., Inc., Rahway, NJ, USA (United States)

Taisho Pharmaceutical (Japan)

Chilworth Technology (United Kingdom)

Johnson & Johnson (United States)

Graeme Semple is an author at Arena Pharmaceuticals (United States) specializing in medicine, pharmacology, and drug discovery.

ORCID

Top concepts

Publications per year

1984–2018

46

Publications

46

A Role for β-Cell-Expressed G Protein-Coupled Receptor 119 in Glycemic Control by Enhancing Glucose-Dependent Insulin Release

Zhi‐Liang Chu, Robert M. Jones, Hongmei He et al. · Endocrinology · 2007 · 292 citations

Discovery of the First Potent and Orally Efficacious Agonist of the Orphan G-Protein Coupled Receptor 119

Graeme Semple, Beatriz Fioravanti, Imelda Calderon et al. · Journal of Medicinal Chemistry · 2008 · 141 citations · Full text

Anxiolytic- and Antidepressant-Like Profile of ATC0065 and ATC0175: Nonpeptidic and Orally Active Melanin-Concentrating Hormone Receptor 1 Antagonists

Shigeyuki Chaki, Takeo Funakoshi, Shiho Hirota-Okuno et al. · Journal of Pharmacology and Experimental Therapeutics · 2005 · 132 citations · Full text

Niacin Lipid Efficacy Is Independent of Both the Niacin Receptor GPR109A and Free Fatty Acid Suppression

Brett Lauring, Andrew K.P. Taggart, James R. Tata et al. · Science Translational Medicine · 2012 · 125 citations

GnRH Antagonists:  A New Generation of Long Acting Analogues Incorporating<i>p</i>-Ureido-phenylalanines at Positions 5 and 6

Guangcheng Jiang, Jacek Stalewski, Robert Galyean et al. · Journal of Medicinal Chemistry · 2000 · 110 citations · Full text

, , +16

Rows per page

1–5 of 46