Imelda Calderon - Concepedia

Author

Imelda Calderon

Arena Pharmaceuticals (United States)

Also Known As

Imelda Calderon

Publications

505

Citations

H-Index

Concepts

All Affiliations

Arena Pharmaceuticals (United States)Cayman Chemical (United States)

About

Imelda Calderon is an author at Arena Pharmaceuticals (United States) specializing in pharmacology, medicine, and drug discovery.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	6	6	243
2	Biochemistry	4	4	214
3	Natural Sciences	1	1	65
4	Chemical Biology	1	1	65
5	Clinical Immunology	1	1	18

Imelda Calderon

Publications

505

Citations

H-Index

Page 1

	Year	Citations
Discovery of the First Potent and Orally Efficacious Agonist of the Orphan G-Protein Coupled Receptor 119 Graeme Semple, Beatriz Fioravanti, Imelda Calderon, Journal of Medicinal Chemistry	2008	141
Discovery of APD334: Design of a Clinical Stage Functional Antagonist of the Sphingosine-1-phosphate-1 Receptor Daniel J. Buzard, Sun Hee Kim, Luis Lopez, ACS Medicinal Chemistry Letters ImmunologyPotent Functional AntagonistInflammationRheumatoid DisorderInflammatory Rheumatic Disease	2014	70
Discovery of fused bicyclic agonists of the orphan G-protein coupled receptor GPR119 with in vivo activity in rodent models of glucose control Graeme Semple, Albert Ren, Beatriz Fioravanti, Bioorganic & Medicinal Chemistry Letters Signal TransductionMolecular PhysiologyBiochemistryFunctional SelectivityMedicine	2011	66
Structural Basis for Inhibition of Human Autotaxin by Four Potent Compounds with Distinct Modes of Binding Adam J. Stein, Gretchen Bain, Pat Prodanovich, Molecular Pharmacology	2015	65
Identification of 4-(Aminomethyl)-6-(trifluoromethyl)-2-(phenoxy)pyridine Derivatives as Potent, Selective, and Orally Efficacious Inhibitors of the Copper-Dependent Amine Oxidase, Lysyl Oxidase-Like 2 (LOXL2) Martin W. Rowbottom, Gretchen Bain, Imelda Calderon, Journal of Medicinal Chemistry Initial Hit 2PharmacotherapyChemical BiologyPharmaceutical ChemistryChemical Derivative	2017	65
Selective Inhibition of Autotaxin Is Efficacious in Mouse Models of Liver Fibrosis Gretchen Bain, Kristen E. Shannon, Fei Huang, Journal of Pharmacology and Experimental Therapeutics	2016	56
Fused tricyclic indoles as S1P1 agonists with robust efficacy in animal models of autoimmune disease Daniel J. Buzard, Sangdon Han, Luis Lopez, Bioorganic & Medicinal Chemistry Letters Clinical ImmunologyInflammationMolecular ImmunologyRobust EfficacyAutoimmune Disease	2012	18
Discovery of a novel trans-1,4-dioxycyclohexane GPR119 agonist series Sangdon Han, Sanju Narayanan, Sun Hee Kim, Bioorganic & Medicinal Chemistry Letters Molecular PharmacologyHeterocyclicBiochemistryMedicinePharmacology	2015	13
Discovery and optimization of 5-fluoro-4,6-dialkoxypyrimidine GPR119 agonists Daniel J. Buzard, Sun Hee Kim, Juerg Lehmann, Bioorganic & Medicinal Chemistry Letters Medicinal Chemistry5-Fluoro-4,6-dialkoxypyrimidine Gpr119 AgonistsMedicineRational Drug DesignPharmacotherapy	2014	11

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