Concepedia

The multifaceted relationship between IL-10 and adaptive immunity: putting together the pieces of a puzzle

Simone Mocellin, Francesco M. Marincola, Carlo Riccardo Rossi, Donato Nitti, Mario Lise

Cytokine & Growth Factor Reviews · 2003 · 248 citations · 180 references

DOI

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References

180

Interleukin-10-deficient mice develop chronic enterocolitis

Ralf Kühn, Jürgen Löhler, D Rennick et al. · Cell · 1993 · 4.3K citations

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A CD4+T-cell subset inhibits antigen-specific T-cell responses and prevents colitis

Hervé Groux, Anne O’Garra, Mike Bigler et al. · Nature · 1997 · 3.6K citations

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Targeted disruption of the mouse transforming growth factor-β1 gene results in multifocal inflammatory disease

Marcia M. Shull, Ilona Ormsby, Ann B. Kier et al. · Nature · 1992 · 3K citations · Full text

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Two types of mouse T helper cell. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones.

David Fiorentino, M W Bond, Timothy R. Mosmann · The Journal of Experimental Medicine · 1989 · 2.7K citations

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Interleukin 10 (IL-10) and viral IL-10 strongly reduce antigen-specific human T cell proliferation by diminishing the antigen-presenting capacity of monocytes via downregulation of class II major histocompatibility complex expression.

René de Waal Malefyt, John B.A.G. Haanen, Hergen Spits et al. · The Journal of Experimental Medicine · 1991 · 1.9K citations · Full text

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