Concepedia

Progress in the proxifan class: heterocyclic congeners as novel potent and selective histamine H3-receptor antagonists

Sven Graßmann, Bassem Sadek, Xavier Ligneau, Sigurd Elz, C. Robin Ganellin, Jean‐Michel Arrang, Jean‐Charles Schwartz, Holger Stark, Walter Schunack

European Journal of Pharmaceutical Sciences · 2002 · 53 citations · 45 references

DOI

Concepts

References

45

Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

Yung-Chi Cheng, William H. Prusoff · Biochemical Pharmacology · 1973 · 12.9K citations

, , +14

The Use of Diethyl Azodicarboxylate and Triphenylphosphine in Synthesis and Transformation of Natural Products

Oyo Mitsunobu · Synthesis · 1981 · 4.1K citations

, , +8

Auto-inhibition of brain histamine release mediated by a novel class (H3) of histamine receptor

Jean‐Michel Arrang, M. Garbarg, Jean‐Charles Schwartz · Nature · 1983 · 1.6K citations

, , +14

Highly potent and selective ligands for histamine H3-receptors

J.M. Arrang, M. Garbarg, J.-C. Lancelo et al. · Nature · 1987 · 902 citations

, , +15

Cloning and Functional Expression of the Human Histamine H<sub>3</sub>Receptor

Timothy W. Lovenberg, Barbara Roland, Sandy J. Wilson et al. · Molecular Pharmacology · 1999 · 700 citations · Full text

, , +16