Concepedia

Is caspase-3 inhibition a valid therapeutic strategy in cerebral ischemia?

Hansruedi Loetscher, Olivier Niederhauser, John A. Kemp, R. Gill

Drug Discovery Today · 2001 · 50 citations · 80 references

DOI

Concepts

References

80

Prevention of Apoptosis by Bcl-2: Release of Cytochrome c from Mitochondria Blocked

Jie Yang, Xuesong Liu, Kapil N. Bhalla et al. · Science · 1997 · 4.9K citations

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The Release of Cytochrome c from Mitochondria: A Primary Site for Bcl-2 Regulation of Apoptosis

Ruth M. Kluck, Ella Bossy‐Wetzel, Douglas R. Green et al. · Science · 1997 · 4.7K citations

, , +17

A Combinatorial Approach Defines Specificities of Members of the Caspase Family and Granzyme B

Nancy A. Thornberry, Thomas A. Rano, Erin P. Peterson et al. · Journal of Biological Chemistry · 1997 · 2.1K citations · Full text

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Apoptosis and necrosis: two distinct events induced, respectively, by mild and intense insults with N-methyl-D-aspartate or nitric oxide/superoxide in cortical cell cultures.

Emanuela Bonfoco, Dimitri Krainc, Maria Ankarcrona et al. · Proceedings of the National Academy of Sciences · 1995 · 2K citations · Full text

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Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice

Keisuke Kuida, Timothy S. Zheng, Songqing Na et al. · Nature · 1996 · 1.9K citations

, , +14