Hansruedi Loetscher

Crystal structure of the soluble human 55 kd TNF receptor-human TNFβ complex: Implications for TNF receptor activation

David W. Banner, A. D’Arcy, Wolfgang Janes et al. · Cell · 1993 · 1.1K citations

Crystal Structure, Signal Transduction, Receptor Tyrosine Kinase +7

Molecular cloning and expression of the human 55 kd tumor necrosis factor receptor

Hansruedi Loetscher, Yu‐Ching E. Pan, Hans‐Werner Lahm et al. · Cell · 1990 · 904 citations

Inflammation, Cytokine, Signal Transduction +9

Increased Brain Penetration and Potency of a Therapeutic Antibody Using a Monovalent Molecular Shuttle

Jens Niewoehner, Bernd Bohrmann, Ludovic Collin et al. · Neuron · 2014 · 580 citations · Full text

Cell-based Drug Delivery, Nanomedicine, Medicine +9

Gantenerumab: A Novel Human Anti-Aβ Antibody Demonstrates Sustained Cerebral Amyloid-β Binding and Elicits Cell-Mediated Removal of Human Amyloid-β

Bernd Bohrmann, Karlheinz Baumann, Jörg Benz et al. · Journal of Alzheimer s Disease · 2012 · 422 citations · Full text

Engineering, Immunology, Elicits Cell-mediated Removal +29

Two human TNF receptors have similar extracellular, but distinct intracellular, domain sequences

Zlatko Dembić, Hansruedi Loetscher, Ueli Gubler et al. · Cytokine · 1990 · 261 citations

Inflammation, Cytokine, Signal Transduction +11