Interaction of cyclosporine and FK506 with diuretics in transplant patients

Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes

Jun S. Liu, Jesse D. Farmer, Willam S. Lane et al. · Cell · 1991 · 4.1K citations

Life Sciences, Biochemistry, Molecular Biology +8

Identification of calcineurin as a key signalling enzyme in T-lymphocyte activation

Neil A. Clipstone · Nature · 1992 · 1.6K citations

Life Sciences, Immunology, Molecular Biology +12

Mutations in the chloride channel gene, CLCNKB, cause Bartter's syndrome type III

David B. Simon, Ranjit S. Bindra, Traci A. Mansfield et al. · Nature Genetics · 1997 · 870 citations

Life Sciences, Genetics, Molecular Genetics +13

Two highly homologous members of the ClC chloride channel family in both rat and human kidney.

S. Kieferle, Peying Fong, Marcelle Bens et al. · Proceedings of the National Academy of Sciences · 1994 · 284 citations

Natural Sciences, Nephrology, Physiology +16

Comparison of acute rapamycin nephrotoxicity with cyclosporine and FK506

Takeshi F. Andoh, Emmanuel A. Burdmann, Nora Fransechini et al. · Kidney International · 1996 · 189 citations · Full text

Medicine, Nephrology, Pharmacology +12