Concepedia

Inactivation of Spry2 accelerates AKT-driven hepatocarcinogenesis via activation of MAPK and PKM2 pathways

Chunmei Wang, Salvatore Delogu, Coral Ho, Susie A. Lee, Bing Gui, Lijie Jiang, Sara Ladu, Antonio Cigliano, Frank Dombrowski, Matthias Evert,

Journal of Hepatology · 2012 · 60 citations · 21 references

Concepts

MedicineMolecular BiologyOncologyCell SignalingMolecular OncologySignal TransductionCancer Cell SignalingCancer ProgressionHepatocellular CarcinomaLiver CancerOncogenic Signaling PathwaysSignal Transduction In CancerMapk SignalingPhosphatidylinositol 3-Kinase-akt PathwayPhosphatidylinositol 3-Kinase-akt SignalingPi3 Kinase-akt SignalingPi3k-akt Signaling Pathway

References

21

Global cancer statistics

Ahmedin Jemal, Freddie Bray, Jacques Ferlay et al. · CA A Cancer Journal for Clinicians · 2011 · 55K citations · Full text

Medicine, Oncology, Cancer Epidemiology +15

Global Cancer Statistics, 2002

Donald Maxwell Parkin, Freddie Bray, Jacques Ferlay et al. · CA A Cancer Journal for Clinicians · 2005 · 18.4K citations · Full text

Medicine, Oncology, Cancer Epidemiology +16

Sorafenib in Advanced Hepatocellular Carcinoma

Josep M. Llovet, Sergio Ricci, Vincenzo Mazzaferro et al. · New England Journal of Medicine · 2008 · 13K citations · Full text

Medicine, Oncology, Pharmacology +12

Sorafenib in Advanced Hepatocellular Carcinoma

재연 정 · 2008 · 5.6K citations

Medicine, Oncology, Pharmacology +12

The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth

Heather R. Christofk, Matthew G. Vander Heiden, Marian H. Harris et al. · Nature · 2008 · 2.8K citations

Medicine, Cancer Biology, Oncology +16