Sara Ladu

Ubiquitous Activation of Ras and Jak/Stat Pathways in Human HCC

Diego F. Calvisi, Sara Ladu, Alexis Gorden et al. · Gastroenterology · 2006 · 728 citations

Medicine, Molecular Medicine, Pathobiology +12

Increased Lipogenesis, Induced by AKT-mTORC1-RPS6 Signaling, Promotes Development of Human Hepatocellular Carcinoma

Diego F. Calvisi, Chunmei Wang, Coral Ho et al. · Gastroenterology · 2010 · 626 citations · Full text

Medicine, Cancer Biology, Oncology +16

Mechanistic and prognostic significance of aberrant methylation in the molecular pathogenesis of human hepatocellular carcinoma

Diego F. Calvisi, Sara Ladu, Alexis Gorden et al. · Journal of Clinical Investigation · 2007 · 395 citations · Full text

Medicine, Molecular Biology, Oncology +17

Yes-Associated Protein Up-regulates Jagged-1 and Activates the NOTCH Pathway in Human Hepatocellular Carcinoma

Darjus F. Tschaharganeh, Xin Chen, Philipp Latzko et al. · Gastroenterology · 2013 · 336 citations · Full text

Medicine, Molecular Biology, Oncology +16

AKT (v-akt murine thymoma viral oncogene homolog 1) and N-Ras (neuroblastoma ras viral oncogene homolog) coactivation in the mouse liver promotes rapid carcinogenesis by way of mTOR (mammalian target of rapamycin complex 1), FOXM1 (forkhead box M1)/SKP2, and c-Myc pathways

Coral Ho, Chunmei Wang, Sandra Mattu et al. · Hepatology · 2011 · 238 citations

Medicine, Molecular Biology, Oncology +14