p21 Downregulation is an important component of PAX3/FKHR oncogenicity and its reactivation by HDAC inhibitors enhances combination treatment

Histone Deacetylase 3 (HDAC3) and Other Class I HDACs Regulate Colon Cell Maturation and p21 Expression and Are Deregulated in Human Colon Cancer

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Life Sciences, Molecular Biology, Oncology +17

p21 ^WAF1 is required for butyrate-mediated growth inhibition of human colon cancer cells

Sonia Y. Archer, Shufen Meng, Amy Shei et al. · Proceedings of the National Academy of Sciences · 1998 · 537 citations · Full text

Medicine, Cancer Biology, Oncology +16

Prognostic Factors and Clinical Outcomes in Children and Adolescents With Metastatic Rhabdomyosarcoma—A Report From the Intergroup Rhabdomyosarcoma Study IV

John C. Breneman, Elizabeth Lyden, Alberto S. Pappo et al. · Journal of Clinical Oncology · 2002 · 470 citations

Medicine, Oncology, Pediatrics +17

Histone Deacetylase Inhibitor Activates the WAF1/Cip1 Gene Promoter through the Sp1 Sites

Yoshihiro Sowa, Tetsuro Orita, Sachie Minamikawa et al. · Biochemical and Biophysical Research Communications · 1997 · 290 citations

Life Sciences, Genetics, Molecular Biology +12

Survival After Relapse in Children and Adolescents With Rhabdomyosarcoma: A Report From the Intergroup Rhabdomyosarcoma Study Group

Alberto S. Pappo, James R. Anderson, William M. Crist et al. · Journal of Clinical Oncology · 1999 · 276 citations

Medicine, Oncology, Pediatrics +15