Butyrate Activates the WAF1/Cip1 Gene Promoter through Sp1 Sites in a p53-negative Human Colon Cancer Cell Line

Katsunori Nakano, Takakazu Mizuno, Yoshihiro Sowa, +11

Journal of Biological Chemistry

Histone Deacetylase Inhibitor Activates the WAF1/Cip1 Gene Promoter through the Sp1 Sites

Yoshihiro Sowa, Tetsuro Orita, Sachie Minamikawa, +4

Biochemical and Biophysical Research Communications

Histone ModificationsChromatinHistone Deacetylase InhibitorChromatin RemodelingEpigenetic Change +9

Sp3, but not Sp1, mediates the transcriptional activation of the p21/WAF1/Cip1 gene promoter by histone deacetylase inhibitor.

Yoshihiro Sowa, Tetsuro Orita, Sachie Minamikawa-Hiranabe, +3

PubMed

Histone ModificationsHistone Deacetylase InhibitorGeneticsCancer BiologyEpigenetics +19

Structural Characterization of Natural and Recombinant Human Granulocyte Colony-Stimulating Factors1

Naoki Kubota, Tetsuro Orita, Kunihiro Hattori, +3

The Journal of Biochemistry

OocyteNatural Human G-csfStructural CharacterizationNatural Hg-csfRecombinant Hg-csf +12

Anti-glypican 3 antibodies cause ADCC against human hepatocellular carcinoma cells

Kiyotaka Nakano, Tetsuro Orita, Jun‐ichi Nezu, +11

Biochemical and Biophysical Research Communications

HepatologyOncogenic AgentMedicineAnti-glypican 3Immunology +5

Construction of a plasmid vector for the regulatable high level expression of eukaryotic genes in <i>Escherichia coli</i>: an application to overproduction of chicken lysozyme

Takeyoshi Miki, Takanori Yasukochi, Hiroko Nagatani, +5

Protein Engineering Design and Selection

Physicochemical and Biological Comparison of Recombinant Human Erythropoietin with Human Urinary Erythropoietin1

Nobuo Imai, Akinori Kawamura, M. Higuchi, +4

The Journal of Biochemistry

UrologyHuman EpoBiochemistryBiological ComparisonAplastic Anemia +11

A novel therapeutic approach for thrombocytopenia by minibody agonist of the thrombopoietin receptor

Tetsuro Orita, Hiroyuki Tsunoda, Naohiro Yabuta, +13

Blood

Generation of a humanized anti-glypican 3 antibody by CDR grafting and stability optimization

Kiyotaka Nakano, Takahiro Ishiguro, Hiroko Konishi, +11

Anti-Cancer Drugs

Cdr GraftingEngineeringGlycobiologyImmunologyBiomedical Engineering +20

Thrombopoietic activity of human interleukin‐6

Toshiro Nagasawa, Tetsuro Orita, J Matsushita, +7

FEBS Letters