Concepedia

Targetable Oncogenic Pathways

Targetable Oncogenic Pathways is a distinct oncogenic signaling cascade that drives tumor progression and possesses molecular characteristics rendering it susceptible to selective inhibition by therapeutic agents.

509

Publications

39.8K

Citations

5.3K

Authors

1.3K

Institutions

Publications per year

2017–2026

281

Parents

Publications

509

Comprehensive molecular characterization of gastric adenocarcinoma

Adam J. Bass, Vésteinn Thórsson, David Van Den Berg et al. · Nature · 2014 · 6.5K citations · Full text

, , +17

Oncogenic pathway signatures in human cancers as a guide to targeted therapies

Andrea Bild, Guang Yao, Jeffrey T. Chang et al. · Nature · 2005 · 2.1K citations

, , +14

Oncogenes, antioncogenes, and the molecular bases of multistep carcinogenesis.

R A Weinberg · PubMed · 1989 · 952 citations

, , +14

Durable tumor regression in genetically altered malignant rhabdoid tumors by inhibition of methyltransferase EZH2

Sarah K. Knutson, Natalie M. Warholic, Tim J. Wigle et al. · Proceedings of the National Academy of Sciences · 2013 · 782 citations · Full text

, , +16

The Structure of Dasatinib (BMS-354825) Bound to Activated ABL Kinase Domain Elucidates Its Inhibitory Activity against Imatinib-Resistant ABL Mutants

John S. Tokarski, John A. Newitt, Chieh Ying J. Chang et al. · Cancer Research · 2006 · 686 citations · Full text

, , +13

1–5 of 509

Authors

5.3K

  1. JF
    Justin F. Gainor

    Massachusetts General Hospital, United States

    5 publications · 196 citations

    5

    h-index

  2. VS
    Vivek Subbiah

    The University of Texas MD Anderson Cancer Center, United States

    4 publications · 164 citations

    4

    h-index

  3. GC
    Giuseppe Curigliano

    European Institute of Oncology, Italy

    4 publications · 164 citations

    4

    h-index

  4. EG
    Elena Garralda

    Vall d'Hebron Institute of Oncology, Spain

    4 publications · 263 citations

    4

    h-index

  5. MP
    Michael P. LaQuaglia

    Memorial Sloan Kettering Cancer Center, United States

    4 publications · 301 citations

    4

    h-index

1–5 of 5.3K

Institutions

1.3K

  1. Harvard University

    Cambridge, United States

    28 h-index

    174 publications

    42.8K citations

  2. Dana-Farber Cancer Institute

    Boston, United States

    27 h-index

    150 publications

    40.3K citations

  3. The University of Texas MD Anderson Cancer Center

    Houston, United States

    27 h-index

    165 publications

    69.9K citations

  4. Massachusetts General Hospital

    Boston, United States

    19 h-index

    78 publications

    5.4K citations

  5. Memorial Sloan Kettering Cancer Center

    New York, United States

    17 h-index

    189 publications

    54.9K citations

  6. Inserm

    Paris, France

    16 h-index

    105 publications

    7.1K citations

  7. Cornell University

    Ithaca, United States

    14 h-index

    96 publications

    6.6K citations

  8. National Cancer Institute

    Bethesda, United States

    13 h-index

    33 publications

    2.6K citations

1–8 of 1.3K

Venues

  1. Oncotarget

    27 publications · 1K citations

    20

    h-index

  2. Oncogene

    22 publications · 1.3K citations

    20

    h-index

  3. Cancer Research

    20 publications · 1.7K citations

    19

    h-index

  4. Nature Communications

    15 publications · 1.5K citations

    15

    h-index

  5. Molecular Cancer Therapeutics

    MCT · 13 publications · 476 citations

    13

    h-index

1–5