Concepedia

Functional inactivation but not structural mutation of p53 causes liver cancer

Hiroyuki Ueda, Stephen J. Ullrich, J. David Gangemi, Catherine A. Kappel, Lien T. Ngo, Mark A. Feitelson

Nature Genetics · 1995 · 370 citations · 46 references

DOI

Concepts

References

46

Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis.

Marc S. Greenblatt, W P Bennett, Monica Hollstein et al. · PubMed · 1994 · 3.5K citations

, , +16

Rapid and sensitive detection of point mutations and DNA polymorphisms using the polymerase chain reaction

Masato Orita, Youichi Suzuki, Takao Sekiya et al. · Genomics · 1989 · 3.5K citations

, , +16

The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation

Jamil Momand, Gerard P. Zambetti, David C. Olson et al. · Cell · 1992 · 3.1K citations

, , +10

Association of Human Papillomavirus Types 16 and 18 E6 Proteins with p53

Bruce A. Werness, Arnold J. Levine, Peter M. Howley · Science · 1990 · 2.6K citations

, , +17

T antigen is bound to a host protein in SY40-transformed cells

David P. Lane, L.V. Crawford · Nature · 1979 · 2.4K citations

, , +10