Concepedia

Regioselective synthesis of folate receptor-targeted agents derived from epothilone analogs and folic acid

Iontcho R. Vlahov, Gregory D. Vite, Paul J. Kleindl, Yu Wang, Hari Krishna R. Santhapuram, Fei You, Stephen Howard, Soong‐Hoon Kim, Francis F.Y. Lee, Christopher P. Leamon

Bioorganic & Medicinal Chemistry Letters · 2010 · 39 citations · 14 references

DOI

Concepts

References

14

Epothilones, a new class of microtubule-stabilizing agents with a taxol-like mechanism of action

Suzanne B. Buck, Sam F. Victory, Richard H. Himes et al. · 1998 · 983 citations

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Epothilons A and B: Antifungal and Cytotoxic Compounds from Sorangium cellulosum (Myxobacteria). Production, Physico-chemical and Biological Properties.

Klaus Gerth, Norbert Bedorf, Gerhard Höfle et al. · The Journal of Antibiotics · 1996 · 628 citations

, , +13

Epothilone A and B—Novel 16‐Membered Macrolides with Cytotoxic Activity: Isolation, Crystal Structure, and Conformation in Solution

Gerhard Höfle, Norbert Bedorf, Heinrich Steinmetz et al. · Angewandte Chemie International Edition in English · 1996 · 514 citations

, , +15

Activities of the Microtubule-stabilizing Agents Epothilones A and B with Purified Tubulin and in Cells Resistant to Paclitaxel (Taxol®)

Richard Kowalski, Paraskevi Giannakakou, Ernest Hamel · Journal of Biological Chemistry · 1997 · 512 citations · Full text

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The glycophospholipid-linked folate receptor internalizes folate without entering the clathrin-coated pit endocytic pathway.

Karen G. Rothberg, Y S Ying, J F Kolhouse et al. · The Journal of Cell Biology · 1990 · 444 citations · Full text

, , +17