Stephen Howard

Design and regioselective synthesis of a new generation of targeted chemotherapeutics. Part 1: EC145, a folic acid conjugate of desacetylvinblastine monohydrazide

Iontcho R. Vlahov, Hari Krishna R. Santhapuram, Paul J. Kleindl et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 125 citations

Medicinal Chemistry, Natural Product Synthesis, Biochemistry +9

Synthesis and application of a poly(ethylene glycol)-antibody affinity ligand for cell separations in aqueous polymer two-phase systems

Kim A. Sharp, Manssur Yalpani, Stephen Howard et al. · Analytical Biochemistry · 1986 · 81 citations

Ethylene Glycol, Cell Separations, Engineering +8

Folate Receptor–Specific Antitumor Activity of EC131, a Folate-Maytansinoid Conjugate

Joseph A. Reddy, Elaine Westrick, Hari Krishna R. Santhapuram et al. · Cancer Research · 2007 · 80 citations

Folate receptor specific anti-tumor activity of folate–mitomycin conjugates

Joseph A. Reddy, Elaine Westrick, Iontcho R. Vlahov et al. · Cancer Chemotherapy and Pharmacology · 2005 · 78 citations

Folate–mitomycin Conjugates, Anti-cancer Agent, Medicine +3

Regioselective synthesis of folate receptor-targeted agents derived from epothilone analogs and folic acid

Iontcho R. Vlahov, Gregory D. Vite, Paul J. Kleindl et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 37 citations

Epothilone Analogs, Biochemistry, Pharmacological Agent +5