Synthesis and antiviral evaluation of benzimidazoles, quinoxalines and indoles from dehydroabietic acid

Selectivity of action of an antiherpetic agent, 9-(2-hydroxyethoxymethyl)guanine

Gertrude B. Elion, Phillip A. Furman, James A. Fyfe et al. · Proceedings of the National Academy of Sciences · 1977 · 1.6K citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +13

A Convenient Synthesis of Ethynylarenes and Diethynylarenes

S. Takahashi, Y. Kuroyama, Kenkichi Sonogashira et al. · Synthesis · 1980 · 1.1K citations

Natural Sciences, Chemistry, Organic Chemistry +5

Synthesis and Biological Activity of Novel Nonnucleoside Inhibitors of HIV-1 Reverse Transcriptase. 2-Aryl-Substituted Benzimidazoles

Thomas Roth, Marshall Morningstar, Paul L. Boyer et al. · Journal of Medicinal Chemistry · 1997 · 370 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

The reaction of vinyl grignard reagents with 2-substituted nitroarenes: A new approach to the synthesis of 7-substituted indoles

Giuseppe Bartoli, Gianni Palmieri, Marcella Bosco et al. · Tetrahedron Letters · 1989 · 327 citations

Natural Sciences, Chemistry, Medicinal Chemistry +9

Design, Synthesis, and Antiviral Evaluations of 1-(Substituted benzyl)-2-substituted-5,6-dichlorobenzimidazoles as Nonnucleoside Analogues of 2,5,6-Trichloro-1-(β-<scp>d</scp>-ribofuranosyl)benzimidazole

Anthony R. Porcari, Rodrigo V. Devivar, Louis S. Kucera et al. · Journal of Medicinal Chemistry · 1998 · 272 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +15