Synthesis and anti-leishmanial activity of heterocyclic betulin derivatives

Discovery of betulinic acid as a selective inhibitor of human melanoma that functions by induction of apoptosis

Emily Pisha, Heebyung Chai, Ik‐Soo Lee et al. · Nature Medicine · 1995 · 886 citations

Life Sciences, Medicinal Chemistry, Pharmacology +14

Drug resistance in Indian visceral leishmaniasis

Shyam Sundar · Tropical Medicine & International Health · 2001 · 580 citations · Full text

Pharmacy, Infectious Diseases, Pharmacotherapy +17

Miltefosine, an Oral Agent, for the Treatment of Indian Visceral Leishmaniasis

T. K. Jha, Shyam Sundar, C.P. Thakur et al. · New England Journal of Medicine · 1999 · 462 citations · Full text

Medicine, Infectious Diseases, Pharmacology +16

Betulinic acid triggers CD95 (APO-1/Fas)- and p53-independent apoptosis via activation of caspases in neuroectodermal tumors.

Simone Fulda, Claudia Friesen, Carsten Scaffidi et al. · PubMed · 1997 · 348 citations · Full text

Life Sciences, Cell Biology, Oncology +17

Generation of Leishmania donovani axenic amastigotes: their growth and biological characteristics

Alain Debrabant, Manju B. Joshi, P. F. P. Pimenta et al. · International Journal for Parasitology · 2003 · 214 citations

Life Sciences, Infectious Diseases, Microbiology +14