Emily Pisha

Discovery of betulinic acid as a selective inhibitor of human melanoma that functions by induction of apoptosis

Emily Pisha, Heebyung Chai, Ik‐Soo Lee et al. · Nature Medicine · 1995 · 881 citations

Tumor Biology, Human Melanoma, Medicine +11

Synthesis of betulinic acid derivatives with activity against human melanoma

Darrick S. H. L. Kim, John M. Pezzuto, Emily Pisha · Bioorganic & Medicinal Chemistry Letters · 1998 · 154 citations

Medicine, Melanoma, Betulinic Acid Derivatives +4

The Major Metabolite of Equilin, 4-Hydroxyequilin, Autoxidizes to an <i>o</i>-Quinone Which Isomerizes to the Potent Cytotoxin 4-Hydroxyequilenin-<i>o</i>-quinone

Fagen Zhang, Yumei Chen, Emily Pisha et al. · Chemical Research in Toxicology · 1999 · 81 citations

A Metabolite of Equine Estrogens, 4-Hydroxyequilenin, Induces DNA Damage and Apoptosis in Breast Cancer Cell Lines

Yumei Chen, Xuemei Liu, Emily Pisha et al. · Chemical Research in Toxicology · 2000 · 66 citations

Oxidative DNA Damage Induced by Equine Estrogen Metabolites:  Role of Estrogen Receptor α

Xuemei Liu, Jiaqin Yao, Emily Pisha et al. · Chemical Research in Toxicology · 2002 · 64 citations