Concepedia

The autophagy/lysosome pathway is impaired in SCA7 patients and SCA7 knock-in mice

Sandro Alves, Florence Cormier‐Dequaire, Martina Marinello, Thibaut Marais, Marie‐Paule Muriel, Florian Beaumatin, Fanny Charbonnier‐Beaupel, Khadija Tahiri, Danielle Seilhean, Khalid El Hachimi,

Acta Neuropathologica · 2014 · 71 citations · 44 references

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44

LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

The EMBO Journal · 2000 · 6.5K citations · Full text

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p62/SQSTM1 Binds Directly to Atg8/LC3 to Facilitate Degradation of Ubiquitinated Protein Aggregates by Autophagy

Serhiy Pankiv, Terje Høyvarde Clausen, Trond Lamark et al. · Journal of Biological Chemistry · 2007 · 4.5K citations · Full text

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Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice

Taichi Hara, Kenji Nakamura, Makoto Matsui et al. · Nature · 2006 · 3.8K citations

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Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease

Brinda Ravikumar, Zdenek Berger, J. Eric Davies et al. · Nature Genetics · 2004 · 2.3K citations

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Axonopathy and Transport Deficits Early in the Pathogenesis of Alzheimer's Disease

Gorazd B. Stokin, Concepción Lillo, Tomás L. Falzone et al. · Science · 2005 · 1.2K citations

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