Alanine Scanning Mutagenesis of Aβ(1-40) Amyloid Fibril Stability

A simple method for displaying the hydropathic character of a protein

Jack Kyte, Russell F. Doolittle · Journal of Molecular Biology · 1982 · 23.1K citations

Life Sciences, Biochemistry, Molecular Biology +12

The Advanced Theory of Statistics.

G. M. Clarke, M. G. Kendall, A. Stuart · Journal of the Royal Statistical Society Series A (General) · 1978 · 6.7K citations

Natural Sciences, Mathematics, Physics +12

The carboxy terminus of the .beta. amyloid protein is critical for the seeding of amyloid formation: Implications for the pathogenesis of Alzheimer's disease

Joseph T. Jarrett, Elizabeth P. Berger, Peter T. Lansbury · Biochemistry · 1993 · 2K citations

Life Sciences, Biochemistry, Molecular Biology +17

A structural model for Alzheimer's β-amyloid fibrils based on experimental constraints from solid state NMR

Aneta T. Petkova, Yoshitaka Ishii, John J. Balbach et al. · Proceedings of the National Academy of Sciences · 2002 · 1.8K citations

Life Sciences, Biochemistry, Biophysics +17

Self-Propagating, Molecular-Level Polymorphism in Alzheimer's ß-Amyloid Fibrils

Aneta T. Petkova, Richard D. Leapman, Zhihong Guo et al. · Science · 2005 · 1.7K citations

Life Sciences, Biochemistry, Neuroscience +17