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In vitro complementation of Tdp1 deficiency indicates a stabilized enzyme-DNA adduct from tyrosyl but not glycolate lesions as a consequence of the SCAN1 mutation

Genome InstabilityCellular EnzymologyBiochemistryGenetic DisorderNatural SciencesBiochemical GeneticsMolecular BiologyScan1 MutationTdp1 DeficiencyMolecular GeneticsVitro ComplementationMedicineMutagenesis