Lawrence F. Povirk

Improved ATM kinase inhibitor KU-60019 radiosensitizes glioma cells, compromises insulin, AKT and ERK prosurvival signaling, and inhibits migration and invasion

Sarah E. Golding, Elizabeth Rosenberg, Nicholas C.K. Valerie et al. · Molecular Cancer Therapeutics · 2009 · 389 citations · Full text

Medicine, Cancer Biology, Oncology +14

Induction of apoptotic DNA fragmentation and cell death in HL-60 human promyelocytic leukemia cells by pharmacological inhibitors of protein kinase C.

W. David Jarvis, Amy Turner, Lawrence F. Povirk et al. · PubMed · 1994 · 355 citations

Life Sciences, Molecular Biology, Pharmacology +16

DNA double-strand breaks and alkali-labile bonds produced by bleomycin

Lawrence F. Povirk, Werner Wübker, Wolfgang Köhnlein et al. · Nucleic Acids Research · 1977 · 292 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +14

Implication of DNA Polymerase λ in Alignment-based Gap Filling for Nonhomologous DNA End Joining in Human Nuclear Extracts

Jae Wan Lee, Luis Blanco, Tong Zhou et al. · Journal of Biological Chemistry · 2003 · 211 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

Conversion of Phosphoglycolate to Phosphate Termini on 3′ Overhangs of DNA Double Strand Breaks by the Human Tyrosyl-DNA Phosphodiesterase hTdp1

Kedar Inamdar, Jeffrey J. Pouliot, Tong Zhou et al. · Journal of Biological Chemistry · 2002 · 200 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17