W. David Jarvis

Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis

Marcel Verheij, Ron Bose, Xin Lin et al. · Nature · 1996 · 1.8K citations

Life Sciences, Cell Biology, Molecular Biology +14

Proinflammatory cytokine expression profile in degenerated and herniated human intervertebral disc tissues

Mohammed F. Shamji, Lori A. Setton, W. David Jarvis et al. · Arthritis & Rheumatism · 2010 · 479 citations

Veterinary Medicine, Immunology, Pathology +17

Induction of apoptotic DNA damage and cell death by activation of the sphingomyelin pathway.

W. David Jarvis, Richard Kolesnick, Frank A. Fornari et al. · Proceedings of the National Academy of Sciences · 1994 · 455 citations

Life Sciences, Cell Biology, Apoptosis +16

Induction of apoptotic DNA fragmentation and cell death in HL-60 human promyelocytic leukemia cells by pharmacological inhibitors of protein kinase C.

W. David Jarvis, Amy Turner, Lawrence F. Povirk et al. · PubMed · 1994 · 355 citations

Life Sciences, Molecular Biology, Pharmacology +16

Induction of apoptosis in U937 human leukemia cells by suberoylanilide hydroxamic acid (SAHA) proceeds through pathways that are regulated by Bcl-2/Bcl-XL, c-Jun, and p21CIP1, but independent of p53

J A Vrana, Roy H. Decker, C R Johnson et al. · Oncogene · 1999 · 286 citations

Life Sciences, Cancer Biology, Oncology +14