Loss of tissue expression of interleukin-10 promotes the disease progression of colorectal carcinoma

Interleukin 10 (IL-10) and viral IL-10 strongly reduce antigen-specific human T cell proliferation by diminishing the antigen-presenting capacity of monocytes via downregulation of class II major histocompatibility complex expression.

René de Waal Malefyt, John B.A.G. Haanen, Hergen Spits et al. · The Journal of Experimental Medicine · 1991 · 1.9K citations · Full text

Life Sciences, Cell Biology, Immunology +15

IL-10 production in cutaneous basal and squamous cell carcinomas. A mechanism for evading the local T cell immune response

J Kim, Robert L. Modlin, R L Moy et al. · The Journal of Immunology · 1995 · 325 citations · Full text

Life Sciences, Dermatology, Immunology +17

Cytokines in pancreatic carcinoma

Behnam Ebrahimi, Susan L. Tucker, Donghui Li et al. · Cancer · 2004 · 315 citations

Life Sciences, Immunology, Oncology +17

Inhibition of interleukin 10 by rituximab results in down-regulation of bcl-2 and sensitization of B-cell non-Hodgkin's lymphoma to apoptosis.

Steve Alas, Christos Emmanouilides, Benjamin Bonavida · PubMed · 2001 · 281 citations

Medicine, Immunology, Oncology +17

Human interleukin-10 can directly inhibit T-cell growth

K Taga, H Mostowski, Giovanna Tosato · Blood · 1993 · 279 citations · Full text

Life Sciences, Cell Biology, Immunology +10