Science · 1989 · 103 citations · 27 references
Natural SciencesBiophysicsMolecular BiologyMolecular BiophysicsMolecular ImagingStructural BiologyAtomic Force MicroscopyBiomolecular InterfacesDna StructureMacromolecular AssemblyMolecular MachinesScanning Probe MicroscopyConductionHelical ConformationHelical Structure AnalysisNanometer-scale ImagingProtein-dna Complex StructureProtein-dna InterfacesProtein-dna Scanning MechanismsReca Protein
Uncoated recA-DNA complexes were imaged with the scanning tunneling microscope (STM). The images, which reveal the right-handed helical structure of the complexes with subunits clearly resolved, are comparable in quality to STM images of metal-coated specimens. Possible conduction mechanisms that allow STM imaging of biological macromolecules are discussed.
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Tunneling through Fatty Acid Salt Monolayers
B. Mann, Hans Kuhn · Journal of Applied Physics · 1971 · 475 citations
Imaging of liquid crystals using a tunnelling microscope
John S. Foster, Jane Frommer · Nature · 1988 · 376 citations
Structure of helical RecA-DNA complexes
Edward H. Egelman, Andrzej Stasiak · Journal of Molecular Biology · 1986 · 244 citations